Central Mechanisms of HPA Axis Regulation by Voluntary Exercise

HPA axis-rhythms.

The hypothalamic-pituitary-adrenal (HPA) axis regulates circulating levels of glucocorticoid hormones, and is the major neuroendocrine system in mammals that provides a rapid response and defense against stress. Under basal (i.e., unstressed) conditions, glucocorticoids are released with a pronounced circadian rhythm, characterized by peak levels of glucocorticoids during the active phase, that...

Stress and the HPA Axis

Stress has long been suggested to be an important correlate of uncontrolled drinking and relapse. An important hormonal response system to stress-the hypothalamic-pituitary-adrenal (HPA) axis-may be involved in this process, particularly stress hormones known as glucocorticoids and primarily cortisol. The actions of this hormone system normally are tightly regulated to ensure that the body can ...

Mindfulness Meditation on HPA-Axis

s: Background: Little has been known about the Hypothalamic Pituitary Adrenal (HPA) axis response to pre-competition stress (PCS) and its response to relaxation therapies such as of Mindfulness Meditation Therapy (MMT) on sports population. In shooting sports good physical as well as psychological condition is highly demanded. Researchers have been performed on the psychophysiological responses...

Genetics of HPA-axis, depression and suicidality.

The ultimate consequence of mental ill-health, suicidal behavior (SB), is a significant problem in most societies of the world. Suicide causes about one million deaths worldwide each year, and 10-20 times more people attempt suicide. The causes of why certain people engage in SB are complex, involving for e.g., both environmental and genetic factors, and interactions in-between. Well-establishe...

The Hpa Axis in Autoimmune Rheumatic Disorders